PNEUMOFOCUS

BULLETIN OF GAVI'S PNEUMOADIP AT JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH
PNEUMOADIP: PNEUMOCOCCAL VACCINES ACCELERATED DEVELOPMENT AND INTRODUCTION PLAN

Volume 3, No. 3 March, 2006

In This Issue
  1. News from the Field: Interview with Dr Felicity Cutts about The Gambia PCV Trial Publication 1-Year Anniversary
  2. Vaccine Financing: Brazil commits $20million to IFFIm
  3. Gordon Brown MP, UK Chancellor of the Exchequer, reiterates commitment to IFFIm and AMC in UK budget report
  4. GAVI Executive Secretary writes about IFFIm and AMC in The Lancet
  5. Vaccine Research: Vaccine efficacy findings of pneumococcal vaccine candidate
  6. Vaccine Communications: A 2nd BBC documentary focusing on pneumococcal disease broadcasts to over 270 million households worldwide
  7. Upcoming Events – See you at Alice Springs!

Interview with Dr Felicity Cutts about The Gambia PCV Trial Publication 1-Year Anniversary
March 25th marks the 1-year anniversary of the landmark publication of The Gambia pneumococcal conjugate vaccine trial in The Lancet. Dr. Felicity Cutts, the Principal Investigator, spoke with PneumoADIP.

Vaccine Financing: Brazil commits $20million to IFFIm
London – March 9, 2006. President Luiz Inacio Lula da Silva announced that Brazil plans to contribute $20 million over 20 years to the International Finance Facility for Immunization (IFFIm). Government pledges to this innovative financing mechanism for immunization now total $4 billion. Seven nations are now committed to the IFFIm: United Kingdom, France, Italy, Spain, Sweden, Norway, Brazil.


Vaccine Financing: Gordon Brown MP, UK Chancellor of the Exchequer, reiterates commitment to IFFIm and AMC in UK budget report
LondonMarch 22, 2006. In the United Kingdom the annual budget report from Gordon Brown MP, reiterated the UK government commitment to tackling global poverty. “The key challenge now is to ensure that the commitments made in 2005 are translated into concrete action to accelerate progress towards the MDGs,” HM Treasury - UK Budget 2006: Report.

Vaccine Financing: Julian Lob-Levyt, executive secretary of GAVI writes success can be achieved through IFFIm and AMC
The Lancet – March 18, 2006. Dr. Lob-Levyt, says that innovative financing mechanisms for immunizations are the key to successful global health partnerships in achieving the Millennium Development Goals.

Vaccine Research: Efficacy findings of pneumococcal vaccine candidate
A recent study examined the efficacy of a novel vaccine that contained polysaccharides from 11 different S. pneumoniae serotypes each conjugated to a recombinant non-lipidated form of H. influenzae-derived protein D. A randomized double-blind efficacy study design was used to assess the efficacy of the candidate vaccine in prevention of acute otitis media caused by pneumococci and non-typable H. influenzae, as well as the effect on the overall burden of disease. Results from this study showed a statistically significant and clinically relevant reduction in episodes of acute otitis media. The results confirmed that the use of the H. influenzae-derived protein D as a carrier protein for pneumococcal polysaccharides - not only allowed protection against pneumococcal otitis, but also against acute otitis media due to non-typable H. influenzae. Prymula et al. Lancet. 2006 Mar; 367: 740-8.

Vaccine communications: A second BBC documentary broadcasts to over 270 million households worldwide
BBC World – February 4 , 2006. BBC World aired The Kill or Cure? Special titled “Pneumococcal Disease: The Battle for a Vaccine" documentary to 270 million households in more than 200 countries and territories. In December 2005, PneumoADIP was proud to participate in the production of a Special BBC World documentary on pneumococcal vaccines. This follow-up film took an in-depth look at the success of routine pneumococcal immunization in North America ( Alaska), highlighted the severe burden of disease in India and Nepal and efforts underway to introduce pneumococcal vaccines where they are needed most. PneumoADIP would like to thank colleagues and families in Alaska, India and Nepal, for making this documentary possible. To view a 4-minute version of this documentary, visit www.preventpneumo.org.

Upcoming Events
If you would like to share meeting dates or any other news with PneumoADIP, please contact Benedicta Kim, hekim@jhsph.edu

ISPPD-5
April 2-6, 2006
Alice Springs, Australia
http://www.isppd5.com

9TH ANNUAL CONFERENCE ON VACCINE RESEARCH
May 8-10, 2006
Baltimore, USA
http://www.nfid.org/conferences/vaccine06

33RD ANNUAL INTERNATIONAL CONFERENCE ON GLOBAL HEALTH
May 30 - June 2, 2006
Washington, DC, USA
http://www.globalhealth.org/conference/